From Petri Dish to Human: Lost in Translation
Room PRMB2021, The Doctoral School
Life Science, Pharmacy and Chemistry, Penrhyn Road Campus, Kingston University
1-2pm Monday 23 February
In an increasingly competitive environment more and more life science research has to be translatable to the therapeutic or diagnostic arenas. The journey from Petri dish to human is a long one and fraught with pitfalls. Even the best ideas have an arduous journey if they are to make it to commercial application. Several high profile studies have recently called into question the reproducibility of life science research which at best undermines the reputation of a lab and at worst can lead to retracted papers and threatens future funding from both academic institutions and industrial collaborators. Additionally avoiding doomed in vivo experiments can save much time and money and has significant ethical benefits. Yet the risk of failure in vivo due to flawed in vitro experiments can be easily reduced by using current best practices and technologies. These range from simple, free to implement practices to the very latest cell biology tools. Such quality control practices and use of standards are commonplace in disciplines such as chemistry and engineering – life science is catching up. This seminar will help you get ahead of the curve.
Nick Amiss: ATCC Outreach Scientist, LGC Group
Nick Amiss studied biochemistry at Warwick University, England, graduating in 2001. He has gained extensive cell culture research experience in market leading companies including:
- GlaxoSmithKline, researching Biopharmaceutical Process Development using bioreactor culture of adherent human cells on microcarriers
- AstraZeneca-MedImmune, researching Preclinical Drug Development and culture process optimisation
- Antisoma, developing novel therapeutics and luminescent cell lines for xenotransplantation
- Infors & Applikon, providing technical training & engineering support for bioreactors
Who Are LGC?
LGC is a leading provider of products and services to improve measurement and quality control within the laboratory. LGC’s offering includes:
- ATCC cell lines, microbes & nucleic acids
- DNA extraction, genotyping and sequencing
- Pharmaceutical, clinical & pharmacopeia reference standards
- Bioanalytical, forensic, drug & toxicology testing
- Proficiency testing
- Analytical method development and validation
- Contract research & program management
- Laboratory management & operations – includes MHRA & BP Commission labs
- Consultancy, training & guidance
Since 2000 LGC have been the exclusive European distributor for ATCC, one of the world’s leading repositories of biological materials. Researchers can access to over 3,000 human, animal & plant cell lines and over 70,000 bacteria, yeast, fungi, protists & viruses. To support this LGC offers a comprehensive Cell Line Authentication programme allowing scientists to meet the requirements set by leading journals to verify the identity of their cell lines and ensure they are free of contaminants. Extensive local technical support and training is available and seminars are delivered internationally.