Dr Hannah Moir
School/Department: Life Sciences
Position: Lecturer in Health & Exercise Prescription
Hannah completed her undergraduate degree in BSc (First Class hons) Science in Health, Exercise and Sport, at the University of Wales Institute, Cardiff (UWIC) in 2005 and was awarded the John Marsden Prize for outstanding achievements.
In 2009, she completed her PhD combining the disciplines of Biochemistry, Exercise Physiology and Immunology at the School of Health Sciences in UWIC. Investigating the biochemical mechanisms of immune suppression and specifically focused on the activation and phosphorylation of AMP-activated Protein Kinase (AMPK).
Whilst at Loughboorugh Univeristy as a Research Associate in Exercise Physiology and Biochemistry, School of Sport & Exercise Sciences, Hannah focused on inflammatory proteins, more specifically, the role of cytokines Interleukin-6 and its receptor in the control of glucose transport and the signalling pathways which are activated and the expression in diabetes.
Hannah is currently investigating the role of nutritional supplements and rehabilitation techniques on muscle damage, inflammation and leukocytosis.
Other research interests lie in the role of omega-3 and -6 polyunsaturated fatty acid supplementation / respiratory training in lung function and asthmatics.
She is also pursuing her interest in clinical conditions and exercise prescription for inflammatory conditions such as diabetes and arthritis.
Educational and Professional Qualifications
- 2010 - present Post Grad Certificate in Learning & Teaching, Kingston University
- 2006 - 2009 PhD in Biomedical Sciences (Exercise Physiology, Immunology & Biochemsitry, University of Wales Institute Cardiff
- 2002 - 2005 BSc (First Class Hons) Science in Health, Exercise & Sport
In relation to health and exercise Hannah's key areas of interest include:-
AMP-Protein Activated Kinase (AMPK)
Inflammation /Immune function
Inflammatory conditions- Diabetes, Arthritis
Physical activity and obesity
Respiratory diseases - Asthma
Dietary /Nutritional supplementations
Cellular signalling mechanisms/pathways
Ergogenic aids in sports performance
Doping in Sports performance (blood biomarkers)
Publications (Peer Reviewed Manuscripts):
Moir, H., Sims, C., Butcher, L.R., Davies, N.A., Hughes, M.G.1, Jones, K.P., and Webb, R. (2010). Exercise-induced Immunosuppression: The Roles of Reactive Oxygen Species and 5AMP-activated Protein Kinase AMPK Dephosphorylation within Immune Cells. Journal of Applied Physiology, 108: 1284-1292.
Moir, H., Butcher, L., Jones, K.P., Hughes, M.G., Neale, H., Jia, H., Al-Ismaily, Z. & Webb, R. (2008). AMPK Inactivation in Mononuclear Cells: A Potential Intracellular Mechanism For Exercise-Induced Immuno-suppression. Applied Physiology, Nutrition and Metabolism, 33: 75-85.
Publications (Peer Reviewed Abstracts):
Moir, Hannah, Jones, Ken P., Hughes, Michael G. & Webb, Richard. (2008). AMPK Inactivation in Mononuclear Cells via an AMP:ATP-independent Mechanism? A Potential Explanation for Exercise-Induced Immunosuppression? FASEB Summer Research Conference- AMPK in Sickness and Health from Molecule to Man, Copenhagen, Denmark.
Moir, H., Butcher, L., Webb, R., Jones, K. & Hughes, M.G (2007). AMPK Deactivation in Mononuclear Cells - A Potential Intracellular Mechanism for Exercise-Induced Immunosuppression. Poster presented at the Annual Conference for the British Academy for Sports and Exercise Science.
Moir, H., Webb, R., Jones, K. & Hughes, M.G. (2007). The Biochemical Mechanism Underpinning Exercise-Induced Immunosuppression. Poster presented at the 4th Annual Conference for the Welsh Institute of Sports, Health & Exercise Science.
Moir, H., Webb, R., Jones, K. & Hughes, M.G. (2006). AMPK Deactivation in Mononuclear Cells - A Potential Intracellular Mechanism for Exercise-Induced Immunosuppression. Poster presented at the 3rd Annual Conference for the Welsh Institute of Sports, Health and Exercise Science.
Module Leader on: LS1450- Skills Acquisition in Sport LS3210- Exercise Prescription LS3160- Growth, Development & Aging Also Lecture on: LS1490- Human Anatomy & Biomechanics LS2440- Physical Activity & Health Promotion LS3500- Physical Activity & Health Promotion LS3190- Sports Injuries LS3440- Doping, Sports Performance & Nutritional Supplements PTM020- Managing Fatigue (in conjunction with St George's Hospital)
Other Professional Activity
Invited Reviewer for:
International Journal of Sports Nutrition and Exercise Metabolism
Member of Professional Socities:
Physiological Society: 2009-Present
The British Association of Sports and Exercise Sciences: 2006-Present
International Society of Exercise and Immunology ISEI Affiliate 2009-Present.
020 8417 2876
Room 126, Penrhyn Road