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Faculty of Science, Engineering and Computing.
Penrhyn Road
Kingston upon Thames
Surrey KT1 2EE

Tel: +44 (0)20 8417 9000

Dr Lori Snyder

School/Department: Life Sciences, Pharmacy & Chemistry
Position: Reader in Biotechnology

Biography

Dr Lori Snyder has been awarded the prestigious W H Pierce Prize by the Society for Applied Microbiology, is a member of the Prokaryotic Division committee of the Microbiology Society, and is an assessment panel chair for the Equality Challenge Unit Athena SWAN awards. Her innovations have been finalists for the Forerunner Prize and BioStars.
Dr. Snyder graduated from Emory University in Atlanta, Georgia, USA in 2001 with a Ph.D. in Microbiology and Molecular Genetics. During her PhD, she conducted genomic analyses at the dawn of bacterial genomics, investigating Neisseria gonorrhoeae and Neisseria meningitidis with Prof. Bill Shafer. In 1995, shortly after the publication of the first bacterial genome sequences, she analyzed and interpreted the incomplete genome sequence data of Neisseria gonorrhoeae and used this to guide experimental research. Her first post-doctoral appointment was at the University of Oxford, where she continued her research on these species. By 2002, Dr. Snyder was designing and using microarrays at the forefront of the transcriptomics field and was the principal designer of the pan-Neisseria microarray as well as aiding in the design and manufacture of other microarrays. In 2007, she was appointed as a Post-doctoral Fellow at the University of Birmingham where she worked with Prof. Mark Pallen and Dr. Nick Loman. She has assisted the Wellcome Trust Sanger Institute with genome annotation and analysis and worked as a bioinformatician supporting the xBASE public genome sequence analysis database.
Dr. Snyder began working with next-generation sequence data in 2007, and since then has been involved in next-generation sequencing projects for Helicobacter canadensis and Helicobacter pullorum, non-pathogenic Neisseria species, Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pneumoniae, Neisseria meningitidis, and Neisseria gonorrhoeae.
In 2009, Dr. Snyder joined Kingston University, expanding upon the University's established expertise in microbiology, molecular biology, and genomics. Dr. Snyder formed the Kingston University Genome Sequencing Facility in 2011, made possible by the investment of Kingston University in the purchase of an Ion Torrent genome sequencer. Using this equipment, Dr. Snyder has sequenced several bacterial genomes to address several biologically relevant questions, including the evolution of genomic changes in Neisseria gonorrhoeae, as well as collaborating with others to investigate cancer genetics, sequence variation is parasites, and biomarkers from circulating nucleic acids.

Educational and Professional Qualifications

  • 1995 - 2001 Ph.D. in Microbiology and Molecular Genetics from Emory University, Atlanta, Georgia, USA
  • 1993 - 1995 M.A. in Biology from The College of William and Mary, Williamsburg, Virginia, USA
  • 1990 - 1993 B.S. in Biology from The College of William and Mary, Williamsburg, Virginia, USA

Research Interests

Dr. Snyder is active in research and in the supervision of undergraduate and postgraduate project students, research degree students, research interns, and visiting scientists. The focus of her research has been built upon her extensive experience in laboratory and bioinformatics investigations of the bacterial pathogens Neisseria gonorrhoeae and Neisseria meningitidis. In Dr. Snyder's research group, these species are being understood through comparative genomic sequence analysis, genome sequence re-annotation, and through long-term culturing of N. gonorrhoeae to determine how chromosomal changes observed in vitro impact the bacteria. In recent years, Dr. Snyder and her research team have identified two novel mechanisms of phase variable gene expression in the pathogenic Neisseria spp., defined the genomic context in which DNA uptake sequences act as transcriptional terminators, and investigated the expression of non-coding RNAs in N. gonorrhoeae. Her research supported by Sparks has been developing a novel treatment to prevent bacterial infections that cause blindness in newborns, featured here. Dr. Snyder is also actively engaged in enterprise activities, currently pursuing three potentially patentable innovations related to the treatment of antibiotic resistant bacterial infections, featured here. Her innovations have been finalists for the Forerunner Prize and BioStars. Those interested in studying for a PhD or MSc by Research with Dr. Snyder should contact her directly to discuss potential projects in her field.

Teaching Area

» Research-led teaching including microbiology, genomics, and transcriptomics lectures, research seminars, workshops, and practical classes for undergraduate and postgraduate students. » Research-based teaching of undergraduate and postgraduate students through research projects contributing to ongoing investigations in my research group, leading to publications. » Development and leadership of a professional placements programme for MSc students. » Reflective assessment of teaching and learning, incorporation of feedback from peers and students, review of pedagogy in light of NSS and TEF and implementation of innovation. » Supervisor of research degrees students, including MSc by Research and PhD. » External examiner for St. George's University of London and the University of Greenwich.

Other Professional Activity

Professional Society Memberships:
» British Society for Antimicrobial Chemotherapy
» European Society of Clinical Microbiology and Infectious Diseases
» Microbiology Society
» Society for Applied Microbiology

Journal Reviewer
» Advances in Bioscience and Bioengineering
» Briefings in Bioinformatics
» British Journal of Pharmacology
» BMC Microbiology
» BMC Evolutionary Biology
» BMC Infectious Diseases
» BMC Genomics
» Clinical and Experimental Ophthalmology
» Clinical Microbiology and Infection
» Database
» FEMS Microbiology Letters
» Genome Biology and Evolution
» Journal of Structural and Functional Genomics
» Microbial Drug Resistance
» Microbiology
» Microorganisms
» Mobile Genetic Elements
» Nucleic Acids Research
» PLoS ONE
» Scientific Reports

Grant Reviewer
» Biotechnology and Biological Sciences Research Council (BBSRC), UK
» British Society for Antimicrobial Chemotherapy (BSAC), UK
» Canada Foundation for Innovation, Canada
» Economic & Social Research Council (ERC)
» European Society for Clinical Microbiology and Infectious Disease (ESCMID), Europe
» Medical Research Council (MRC), UK
» Meningitis Now, UK
» National Health and Medical Research Council, Australia
» National Science Foundation (NSF), USA.

Conference invited speaker
» Genomics and Molecular Medicine Bioinformatics Congress 2017. London.
» Oxford Global Annual Next Generation Sequencing Asia Congress 2016. Singapore.
» Institute of Biomedical Science Congress (IBMS) 2015. Birmingham.
» Oxford Global Annual Next Generation Sequencing Congress 2014. London.
» GTC Nucleic Acids Summit. Bioinformatics & Pharmacogenomics 2014. San Diego, California, USA.
» SelectBio European Lab Automation 2014. Barcelona, Spain.
» Oxford Global Annual Next Generation Sequencing Asia Congress 2013. Singapore.
» Society for Applied Microbiology Summer Conference 2013. Cardiff.
» Oxford Global Annual Next Generation Sequencing Congress 2012. London.
» SelectBio European Lab Automation 2012. Hamburg, Germany.
» Life Technologies Ion Torrent User Meeting 2012. Faro, Portugal.
» SMi Next-Generation Sequencing Conference 2012. London.
» Society for Applied Microbiology PECS Conference 2012. London.
» Informa LifeSciences Next Generation Sequencing 2012. Prague, Czech Republic.
» Oxford Global Annual Next Generation Sequencing Congress 2011. London.
» 21st European Conference for Clinical Microbiology and Infectious Disease (ECCMID) / 27th International Congress of Chemotherapy (ICC) 2011. Milan, Italy.
» British Society for Antimicrobial Chemotherapy, Antibiotic Resistance Mechanisms 2010. Birmingham.
» Oxford Global Annual Next Generation Sequencing Congress 2009. London.


Outreach Activities
» Work experience for students from Tiffin School and Surbiton High School. July 2015 & 2016.
» Surbiton High School Career Fair. Presentation and one-to-one sessions. October 2015.
» London Big Bang Fair 2014. Over 200 school children participated in our virtual Microbiology lab, Diagnostics lab, and Genomics lab to identify the mystery bacterial infection and find the right treatment.
» Biology Week discussions with students at Holy Trinity School. Crawley. October 2013 & 2015.
» Kingston Connections speaker. Rose Theatre. Kingston upon Thames. June 2013 & 2014.
» Café Scientifique speaker. Woody's. Kingston upon Thames. June 2013 & Feb. 2016.
» BA Festival of Science perspectives participant. Liverpool. September 2008.


+Publications

    +Professional Experience

Details

Email:
L.Snyder@kingston.ac.uk

Phone:
020 8417 2003

Location:
PRMB1011